Inkcazelo emfutshane:
Inombolo yeCAS: 24390-14-5
Ifomula yemolekyuli:C24H31ClN2O9
ubunzima bemolekyuli: 526.97
Ubume beKhemikhali:
| Ulwazi olusisiseko | |
| Igama lemveliso | Doxycycline hyclate |
| IBanga | ibakala lamayeza |
| Imbonakalo | tyheli, umgubo wekristale oyihygroscopic |
| Isivavanyi | 99% |
| Beka ubomi kwishelufa | iminyaka eyi-2 |
| Ukupakisha | 25kg/ibhokisi |
| Imeko | igcinwe kwindawo epholileyo neyomileyo |
Inkcazo yeDoxycycline Hyclate
I-Doxycycline ilungu leqela le-antibiotics ye-tetracycline, kwaye isetyenziselwa ukuphatha izifo ezahlukeneyo.I-Doxycycline hyclate i-yellow, i-hygroscopic crystalline powder, i-soluble ngokukhululekile emanzini nakwi-methanol, i-soluble ngokukhawuleza kwi-ethanol (ipesenti ezingama-96), inyibilika kwizisombululo zealkali hydroxides kunye necarbonates.
I-Doxycycline Hyclate luhlobo lwetyuwa lwe-hyclate lwe-doxycycline, liyi-antibiotics ye-tetracycline ebanzi.Ithintela ukuhlanganiswa kweeprotheyini zebhaktheriya ngokuzibophelela kwi-ribosomes.I-Doxycycline iphinda inqande ngokukhethayo i-matrix ye-metalloproteinase-8 (MMP-8) kunye ne-MMP-13 phezu kwe-MMP-1 kunye ne-50, i-60, kunye ne-5% inhibition, ngokulandelelana, xa isetyenziswe kwi-concentration ye-30 μM.Ingasetyenziswa njengomlawuli weenkqubo zokubonisa imfuza engakholelekiyo apho intetho ixhomekeke nokuba kukho (Tet-On) okanye ukungabikho (Tet-Off) yedoxycycline.Iifomyula eziqukethe i-doxycycline zisetyenzisiwe kunyango losulelo lwebhaktheriya kunye nokuthintela isifo seengcongconi.
Ukusetyenziswa kwe-Doxycycline hyclate
I-Doxycycline hyclate ilungu leqela le-antibiotics ye-tetracycline, kwaye isetyenziswa ngokuqhelekileyo ukunyanga izifo ezahlukeneyo.Isetyenziselwa unyango lwe-chlamydia, i-rickettsia, i-mycoplasma kunye nezinye izifo ze-spirochete.Ikwasetyenziselwa ukuthintela i-matrix metalloproteinases kwiidosi ze-subantimicrobial.Inqanda i-matrix metalloproteinases kwiidosi ze-subantimicrobial.
I-Doxycycline hyclate yi-synthetic oxytetracycline derivative.Isetyenziselwe ukuphelisa i-Borrelia burgdorferi kunye ne-Anaplasma phagocytophilum kumadama eempuku kunye nokuphelisa i-Ixodes scapularis amakhalane.I-spectrum inhibitor ebanzi esetyenziselwa ukuvimbela i-matrix metalloproteinases (MMP), njengohlobo lwe-collagenase ye-1 kwizifundo zokupholisa amanxeba kunye nokulungiswa kwezicubu.
