Inkcazelo emfutshane:
Inombolo yeCAS: 15307-79-6
Ifomula yemolekyuli:C14H10Cl2NNaO2
ubunzima bemolekyuli:318.13
Ubume beKhemikhali:
| Ulwazi olusisiseko | |
| Igama lemveliso | Diclofenac sodium |
| IBanga | ibakala lamayeza |
| Imbonakalo | Umgubo omhlophe |
| Isivavanyi | 99% |
| Beka ubomi kwishelufa | iminyaka eyi-2 |
| Ukupakisha | 25kg/ibhokisi |
| Imeko | Gcina isikhongozeli sivaliwe kwindawo eyomileyo nengena umoya. |
Inkcazo yeDiclofenac sodium
Imigangatho yesibini ye-Pharmaceutical yesicelo kulawulo lomgangatho, inikezela iilebhu ze-pharma kunye nabavelisi ngendlela efanelekileyo kunye neendleko ezisebenzayo ekulungiseleleni imigangatho yokusebenza kwendlu.
Ihlelwe phantsi kweklasi ye-non-steroidal anti-inflammatory drugs (NSAIDs).Ibonisa imisebenzi yokuvuvukala, i-analgesic kunye ne-antipyretic.I-Diclofenac Sodium yindlela yetyuwa yesodium ye-diclofenac, i-benzene acetic acid ephuma kunye ne-nonsteroidal anti-inflammatory drug (NSAID) ene-analgesic, antipyretic kunye ne-anti-inflammatory activity.
I-sodium ye-Diclofenac kudala isetyenziselwa ukunyanga iintlungu ezibuhlungu kunye nokudumba, kwaye iyasebenza kwiintlobo ezahlukeneyo zentlungu.
Isicelo seklinikhi malunga ne-Diclofenac sodium
Izilingo zeklinikhi zibonise ukuphumelela kwe-analgesic ye-diclofenac sodium ngokubhekiselele ekunciphiseni i-moderation ukuya kwiintlungu ezinzima emva kokuhlinzwa kwizigulane ezenza utyando lwamazinyo okanye utyando oluncinci lwamathambo.I-subcutaneous diclofenac sodium nayo yakhulula ngokufanelekileyo imodareyitha ukuya kwiintlungu ezinzima ze-neuropathic, ezinxulumene nomhlaza okanye hayi.I-sodium ye-Diclofenac yayinyamezeleke kakuhle kwizilingo zeklinikhi, kunye ne-injection-site reactions phakathi kweziganeko ezibi kakhulu ezichazwe ngokuqhelekileyo.I-sodium ye-Diclofenac iboniswa kunyango lwe-rheumatoid arthritis, i-osteoarthritis, kunye ne-ankylosing spondylitis.
Iinkqubo zokwenza malunga neDiclofenac sodium
Iindlela ezibekayo zesenzo se-diclofenac zingabandakanya ukuvinjelwa kwe-leukotriene synthesis, inhibition of phospholipase A2, ukumodareyithwa kwamanqanaba e-arachidonic acid, ukuvuselela iziteshi ze-adenosine triphosphate-sensitive potassium ngokusebenzisa i-L-arginine-nitric oxide-cyclic guanosine monophosphate pathway kunye ne-centrally mediated pathway. iindlela ze-neuropathic.Ezinye iindlela ezikhulayo zesenzo zingabandakanya inhibition ye-peroxisome proliferator activated receptor-c, ukunciphisa i-plasma kunye ne-synovial substance P kunye namanqanaba e-interleukin-6, ukuvinjelwa kwe-receptor ye-thromboxane-prostanoid kunye nokuvinjelwa kwe-acid-sension ion channels.
