Inkcazelo emfutshane:
Inombolo yeCAS: 126-07-8
Ifomula yemolekyuli:C17H17ClO6
ubunzima bemolekyuli: 352.77
Ubume beKhemikhali:
| Ulwazi olusisiseko | |
| Igama lemveliso | Griseofulvin |
| IBanga | ibakala lamayeza |
| Imbonakalo | Umgubo omhlophe ukuya kumthubi-mhlophe |
| Isivavanyi | 99% |
| Beka ubomi kwishelufa | iminyaka eyi-2 |
| Ukupakisha | 25kg/ibhokisi |
| Uphawu | Ayinyibiliki ngokoqobo emanzini, inyibilika ngokukhululekileyo kwi-dimethylformamide nakwi-tetrachloroethane, inyibilika kancinane kwi-anhydrous ethanol nakwi-methanol. |
| Imeko | Gcina isikhongozeli sivaliwe kwindawo eyomileyo nengena umoya. |
Inkcazo jikelele yeGriseofulvin
I-Griseofulvin yiklasi ye-non-polyene antibiotics antifungal;inokuthintela ngamandla i-mitosis yeseli yefungal kwaye iphazamise ukuhlanganiswa kwe-DNA yefungal;inokubophelela kwi-tubulin ukukhusela ukwahlukana kweeseli zefungal.Isetyenziswe kunyango lweklinikhi ukususela ngo-1958 kwaye ngoku isetyenziswa ngokubanzi ukunyanga izifo zefungal zesikhumba kunye ne-stratum corneum kunye neziphumo ezinamandla zokuthintela kwi-Trichophyton rubrum kunye ne-Trichophyton tonsorans, njl. unyango lwezifo zokungunda kwesikhumba kunye ne-cuticle, kodwa zikwasetyenziswa kwezolimo ukukhusela kunye nokunyangwa kwezifo zefungal;umzekelo, inokusebenza okukhethekileyo ekuphatheni uhlobo lwe-candidiasis kwi-apula enokubangela usulelo ngexesha lokuvota.
Iimpawu zeGriseofulvin
Kwezamayeza,le mveliso ilungele unyango lwe intshulube ezahlukeneyo, kuquka tinea capitis, tinea barbae, tinea umzimba, jock itch, tinea unyawo kunye onychomycosis.Iindidi ezahlukeneyo tinea ezikhankanywe zibangelwa ngumngundo ezahlukeneyo kuquka Trichophyton rubrum, Trichophyton tonsorans, Trichophyton mentagrophytes, Fingers Trichophyton, njl, kunye Microsporon audouini, Microsporon canis, Microsporon gypseum kunye Epidermophyton floccosum, njl ngenxa.Le mveliso ayifanelekanga kunyango kwiimeko ezincinci, iimeko zosulelo lwendawo kunye neemeko ezinokunyangwa nge-topical agents antifungal.IGriseofulvin ayisebenzi ekunyangeni usulelo lweentlobo ngeentlobo zomngundo ezifana neCandida, iHistoplasma, Actinomyces, iintlobo zeSporothrix, Blastomyces, Coccidioides, Nocardio kunye neCryptococcus iintlobo kunye nokunyanga tinea versicolor.
Kwezolimo,le mveliso yaziswa kuqala nguBrian etal (1951) ukulawula izifo zezityalo.Ngokwezifundo zangaphambili, ingasetyenziselwa ukuthintela isifo se-melon (melon) kwi-vine blight, isifo se-crack spread, blight blight, i-anthracnose, i-apile blossom rot, i-apple blossom rot, ukubola kwe-apile, ukubola kwe-apula, i-cucumber downy mildew, i-strawberry grey mold, i-gourds ejingayo. , powdery mildew of roses, chrysanthemums powdery mildew, rot flower lettuce, i-tomato blight yasekuqaleni, i-tulip fire blight kunye nezinye izifo zefungal.
