Inkcazelo emfutshane:
Inombolo yeCAS: 137-88-2
Ifomula yemolekyuli: C14H20Cl2N4
ubunzima bemolekyuli:315.24
Ubume beKhemikhali:
| Ulwazi olusisiseko | |
| Igama lemveliso | I-Oxytetracycline hydrochloride |
| IBanga | Ibakala lokutyisa/ibakala lePharma |
| Imbonakalo | Umgubo weCrystalline otyheli |
| Isivavanyi | 99% |
| Beka ubomi kwishelufa | iminyaka eyi-2 |
| Ukupakisha | 25kg/igubu |
| Imeko | Gcina kwindawo epholileyo, eyomileyo, emnyama kwisitya esivalwe ngokuqinileyo okanye isilinda. |
Ukuqaliswa kwe-Oxytetracycline hydrochloride
I-Oxytetracycline hydrochloride yinkompawundi emthubi, ekrakra, yikristale.Isiseko se-amphoteric sinyibilika kancinane kuphela emanzini kwaye sinyibilika kancinane etywaleni.Ayinavumba kwaye ayizinzile emoyeni kodwa iba mnyama xa ichanabeke kwilanga elinamandla.Ityuwa yehydrochloride ngumgubo otyheli ozinzileyo okrakra ngaphezu kwesiseko sasimahla.Inyibilika ngakumbi emanzini, i-1 g inyibilika kwi-2 mL, kwaye inyibilika ngakumbi etywaleni kunesiseko sasimahla.Zombini iikhompawundi zingasebenzi ngokukhawuleza nge-alkali hydroxides kunye nezisombululo ze-asidi ezingaphantsi kwe-pH 2. Zombini iifom ze-oxytetracycline zifunxwa ngokukhawuleza nangokulinganayo ukusuka kwindlela yokugaya, ngoko ke inzuzo yokwenyani kuphela isiseko samahhala esinikezelayo ngaphezu kwetyuwa ye-hydrochloride kukuba ayikrakra kakhulu. .I-Oxytetracycline hydrochloride iphinda isetyenziswe kwi-parenteralaladministration (i-intravenously kunye ne-intramuscularly).
Ukusetyenziswa kwe-Oxytetracycline hydrochloride
I-Oxytetracycline hydrochloride yityuwa elungiswe kwi-oxytetracycline ethatha inzuzo ye-dimethyl amino iqela elisisiseko elivelisa ngokukhawuleza ukwenza ityuwa kwi-hydrochloric acid solutions.I-hydrochloride yindlela ekhethwayo yokwenziwa kwezicelo zamachiza.Njengazo zonke i-tetracyclines, i-oxytetracycline ibonisa i-antibacterial spectrum ebanzi kunye nomsebenzi we-antiprotozoan kwaye yenza ngokuzibophelela kwi-30S kunye ne-50S ye-ribosomal sub-units, ukuvimba iprotheni synthesis.
I-Oxytetracycline sisibulali-zintsholongwane esiboniswa kunyango losulelo olubangelwa yiGram positive kunye neGram negative microorganisms ezifana neMycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, kunye neDiplococcus pneumoniae.Isetyenziswe kwizifundo kwi-oxytetracycline-resistance gene (otrA).I-Oxytetracycline hydrochloride isetyenziselwa ukufunda i-phagosome-lysosome (PL) fusion kwii-P388D1 cells1 kunye ne-antibiotic susceptibility of Mycoplasma bovis isolate.
