Inkcazelo emfutshane:
Inombolo yeCAS: 137-88-2
Ifomula yemolekyuli: C14H20Cl2N4
ubunzima bemolekyuli: 315.24
Ubume beKhemikhali:
| Ulwazi olusisiseko | |
| Igama lemveliso | I-Oxytetracycline hydrochloride |
| IBanga | Ibakala lokutyisa/ibakala lePharma |
| Imbonakalo | Umgubo weCrystalline otyheli |
| Isivavanyi | 99% |
| Beka ubomi kwishelufa | iminyaka eyi-2 |
| Ukupakisha | 25kg/igubu |
| Imeko | Gcina kwindawo epholileyo, eyomileyo, emnyama kwisitya esivalwe ngokuqinileyo okanye isilinda. |
Ukuqaliswa kwe-Oxytetracycline hydrochloride
I-Oxytetracycline hydrochloride yinkompawundi emthubi, ekrakra, yikristale. Isiseko se-amphoteric sinyibilika kancinane kuphela emanzini kwaye sinyibilika kancinane etywaleni. Ayinavumba kwaye ayizinzile emoyeni kodwa iba mnyama xa ichanabeke kwilanga elinamandla.Ityuwa yehydrochloride ngumgubo otyheli ozinzileyo okrakra ngaphezu kwesiseko sasimahla. Inyibilika ngakumbi emanzini, i-1 g yokunyibilika kwi-2 mL, kwaye inyibilika ngakumbi etywaleni kunesiseko sasimahla. Zombini iikhompawundi zingasebenzi ngokukhawuleza nge-alkali hydroxides kunye nezisombululo ze-asidi ezingaphantsi kwe-pH 2. Zombini iifom ze-oxytetracycline zifunxwa ngokukhawuleza kwaye ngokulinganayo ngokulinganayo kwi-digestive tract, ngoko ke inzuzo yokwenene yodwa isiseko samahhala sinikezela ngaphezu kwetyuwa ye-hydrochloride kukuba ayikrakra kakhulu. . I-Oxytetracycline hydrochloride iphinda isetyenziswe kwi-parenteralaladministration (i-intravenously kunye ne-intramuscularly).
Ukusetyenziswa kwe-Oxytetracycline hydrochloride
I-Oxytetracycline hydrochloride yityuwa elungiselelwe kwi-oxytetracycline ithatha inzuzo yeqela elisisiseko le-dimethyl amino elikhupha ngokukhawuleza ukwenza ityuwa kwizisombululo ze-hydrochloric acid. I-hydrochloride yindlela ekhethwayo yokwenziwa kwezicelo zamachiza. Njengazo zonke i-tetracyclines, i-oxytetracycline ibonisa i-antibacterial spectrum ebanzi kunye nomsebenzi we-antiprotozoan kwaye yenza ngokuzibophelela kwi-30S kunye ne-50S ye-ribosomal sub-units, ukuvimba iprotheni synthesis.
I-Oxytetracycline sisibulali-zintsholongwane esiboniswa kunyango losulelo olubangelwa yiGram positive kunye neGram negative microorganisms ezifana neMycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, kunye neDiplococcus pneumoniae. Isetyenziswe kwizifundo kwi-oxytetracycline-resistance gene (otrA). I-Oxytetracycline hydrochloride isetyenziselwa ukufunda i-phagosome-lysosome (PL) fusion kwiiseli ze-P388D11 kunye ne-antibiotic susceptibility of Mycoplasma bovis isolate.
