Inkcazelo emfutshane:
Inombolo yeCAS: 70458-96-7
Ifomula yemolekyuli:C16H18FN3O3
ubunzima bemolekyuli:319.33
Ubume beKhemikhali:
| Ulwazi olusisiseko | |
| Igama lemveliso | Norfloxacin |
| IBanga | Yondla iBanga |
| Imbonakalo | Umgubo wekristale omhlophe ukuya kumthubi |
| Isivavanyi | 99% |
| Beka ubomi kwishelufa | iminyaka eyi-2 |
| Ukupakisha | 25kg/ibhokisi |
| Uphawu | Inyibilika kancinane kakhulu emanzini, inyibilika kancinane kwi-acetone nakwi-ethanol |
| Ugcino | Gcina kwindawo emnyama, itywinwe kwindawo eyomileyo, ubushushu beGumbi |
Inkcazo yeNofloxacin
INofloxacin yeyesizukulwana sesithathu se-quinolone antibacterial agent ephuhliswe yiJapan Kyorin Company ngo-1978. Ineempawu ze-antibacterial spectrum ebanzi kunye nomsebenzi onamandla wokulwa neebhaktheriya. Inefuthe elinamandla lokulwa ne-antibacterial ngokumelene ne-Escherichia coli, i-pneumobacillus, i-Aerobacter aerogenes, kunye ne-Aerobacter cloacae, i-Proteus, i-Salmonella, i-Shigella, i-Citrobacter kunye ne-Serratia. Isetyenziswa ngokweklinikhi ukunyanga uhlobo olunokuchaphazeleka olubangela usulelo lwenkqubo yomchamo, amathumbu, inkqubo yokuphefumla, utyando, i-gynecology, i-ENT kunye ne-dermatology. Ingasetyenziselwa unyango lwe-gonorrhea.
Iyeza elichasayo losulelo
I-Norfloxacin lichiza le-quinolone-class-anti-infective kunye neqondo eliphezulu lomsebenzi we-antibacterial ngokuchasene ne-Escherichia coli, i-Shigella, i-Salmonella, i-Proteus, i-Pseudomonas aeruginosa kunye nezinye iibhaktheriya zegram-negative kunye nefuthe elihle kakhulu lokulwa ne-Staphylococcus aureus, i-pneumococcus kunye nezinye iintsholongwane ze-Gramcoccus. iibhaktheriya ezilungileyo. Indawo yayo enkulu yesenzo ikwibhaktiriya ye-DNA gyrase, ebangela ukuqhekeka okukhawulezileyo kwebhaktheriya ye-DNA helix kwaye inqande ngokukhawuleza ukukhula kwebhaktiriya kunye nokuzala, ekugqibeleni ibulale ibhaktheriya. Ngaphezu koko, inamandla okungena okunamandla kwiindonga zeseli ukwenzela ukuba ibe nefuthe elinamandla le-bactericidal kunye nokuvuselela okuncinci kwi-gastric mucosa. I-Norfloxacin yi-agent ye-synthetic chemotherapeutic ehlala isetyenziselwa ukunyanga izifo eziqhelekileyo kunye nosulelo oluntsonkothileyo lomjelo womchamo.
Ukusetyenziswa kweKlinikhi
Usulelo oluntsonkothileyo nolungantsonkothanga lwendlela yomchamo (kubandakanya iprophylaxis kwizifo eziphindaphindiweyo), i-prostatitis, i-gonorrhea engantsonkothanga, iGastroenteritis ebangelwa yiSalmonella, Shigella kunye neCampylobacter spp., Vibrio cholerae kunye neConjunctivitis (ukulungiswa kwamehlo)
