Inkcazelo emfutshane:
Inombolo yeCAS: 70288-86-7
Ifomula yemolekyuli:C48H74O14
ubunzima bemolekyuli: 875.09
Ubume beKhemikhali:
| Ulwazi olusisiseko | |
| Igama lemveliso | Ivermectin |
| IBanga | IBanga lokuTyayo/iBanga lokuFundisa/iBanga lezaMachiza |
| Imbonakalo | Umgubo omhlophe |
| Isivavanyi | 99% |
| Beka ubomi kwishelufa | iminyaka eyi-2 |
| Ukupakisha | 25kg/ibhokisi |
| Imeko | Indawo epholileyo eyomileyo |
Inkcazo ye-Ivermectin
Ivermectin i agent antiparasitic esebenzayo kunyango onchocerciasis, okanye "umlambo blindness".Ekubeni i-ivermectin isebenza ukuthintela umbungu omdala ekuveliseni i-microfilariae, kufuneka isetyenziswe kanye okanye kabini ngonyaka.
Iziphumo ze-Ivermectin
Ivermectin ngumgubo omhlophe okanye okhanyayo otyheli wecrystalline kwaye unyibilika kwi-methyl alcohol, ester kunye ne-hydrocarbon enuka kamnandi kodwa amanzi.Ivermectin luhlobo lweyeza lokubulala iintsholongwane elinempembelelo yokuqhuba nokubulala kwiinematodes, izinambuzane kunye namangolwane.Isitofu kunye ne-troche eyenziwe nge-ivermectin isetyenziswa ikakhulu kunyango lwe-nematode yesisu semfuyo, i-hypodermosis yenkomo, impethu yethole, impukane yempumlo yeegusha, kunye nokhwekhwe lweegusha neehagu.Ngaphandle koko, i-ivermectin inokufumaneka kunyango lwe-nematodes yesityalo-iparasitic (i-ascarid, i-lungworm) kwiinkukhu.Ukongeza, isenokwenziwa isitshabalalisi sezolimo sokubulala amangolwane, iplutella xylostella, umbungu wekhaphetshu, umgodi wamagqabi, iphylloxera kunye nenematode ezizifunxi-gazi kwizityalo.Olona phawu lubalaseleyo lwesi sibulali zinambuzane kukuba sineziphumo ebezingalindelekanga ezincinci kwaye sinokuqhuba sibulale iintlobo ezininzi zezifunxi-gazi ngaphakathi nangaphandle ngexesha.
Pharmacology of Ivermectin
Ivermectin yeyodidi lwezinto ezibizwa ngokuba zii-avermectines.Ezi lactones macrocylic eziveliswa ukubiliswa kwe actinomycete, Streptomyces avermitilis.Ivermectin yiarhente ebanzi esebenzayo ngokuchasene ne-nematodes kunye ne-arthropods kwizilwanyana zasekhaya kwaye ke isetyenziswa ngokubanzi kunyango lwezilwanyana.[1].Ichiza laqalwa okokuqala kwindoda ngo-1981. Ibonakaliswe ukuba iyasebenza ngokuchasene noluhlu olubanzi lwe-nematodes ezifana ne-Strongyloides sp., Trichuris trichiura, Enterobius vermicularis, Ascaris lumbricoides, i-hook worms kunye ne-Wuchereria bancrofti.Nangona kunjalo, ayinayo impembelelo kwi-flukes yesibindi kunye ne-cestodes[2].
