Inkcazelo emfutshane:
Inombolo ye-CAS: 112811-59-3
Ifomula yemolekyuli:C19H22FN3O4
ubunzima bemolekyuli: 375.39
Ubume beKhemikhali:
| Ulwazi olusisiseko | |
| Igama lemveliso | 112811-59-3 |
| IBanga | IBanga lezamayeza |
| Imbonakalo | Mhlophe ukuya kwi-Off-Mhlophe icrystalline powder |
| Isivavanyi | 99% |
| Beka ubomi kwishelufa | iminyaka eyi-2 |
| Ukupakisha | 25kg/igubu |
| Ugcino | Gcina kwindawo epholileyo eyomileyo |
Ingcaciso yeMveliso
I-Gatifloxacin yeyodidi lwamachiza aziwa ngokuba yi-quinolone antibiotics kwaye isetyenziselwa ukunyanga izifo ze-sinus, imiphunga, okanye i-urinary tract kunye ne-bacterial infection. kunye ne-gatifloxacin ziquka isicaphucaphu, i-vaginitis (ukucaphuka okanye ukudumba kwelungu lobufazi), urhudo, intloko ebuhlungu, isiyezi, kunye nokubetha kwentliziyo okungaqhelekanga. Ngokuqhelekileyo, i-gatifloxacin isetyenziswe kubantu abangaphenduliyo kwezinye iindlela zonyango ze-AOM.
Kwisifundo esinye, i-gatifloxacin yafaniswa ne-amoxicillin / i-clavulanate kunyango lwe-otitis media (OM) kunye ne-AOM kwiintsilelo zonyango kubantwana.Iintsana ezingamakhulu amathathu namashumi amahlanu anesine kunye nabantwana abane-OM okanye i-AOM ephindaphindiweyo bafumana i-gatifloxacin okanye i-amoxicillin / clavulanate. Iziphumo zabonisa ukuba omabini amachiza anyamezeleke kakuhle; esona siphumo sixhaphakileyo sisirhudo.Abaphandi bagqibe kwelokuba unyango nge-gatifloxacin kanye yonke imihla lwalusebenza njenge-amoxicillin/clavulanate kabini yonke imihla.Kwezinye iincwadi zonyango, i-gatifloxacin iqatshelwe njengendlela yonyango lodidi lwesithathu kwi-AOM.
Ukusetyenziswa kwezamayeza
I-spectrum ibandakanya i-Acinetobacter spp kunye ne-Aeromonas spp, kodwa ayisebenzi kakhulu ngokuchasene ne-Ps. i-aeruginosa kunye nezinye iintonga ezingenayo i-Gram-negative. Isebenza ngakumbi kwiintlobo ze-staphylococci ezinokuthi zichaphazeleke kwi-methicillin kuneentlobo ezikwaziyo ukumelana ne-methicillin. Ikwasebenza ngokuchasene neChlamydia, Mycoplasma kunye neLegionella spp. kwaye unomsebenzi othile ochasene ne-anaerobes.
Iphantse ifunxe ngokupheleleyo xa inikwe ngomlomo kwaye isasazwa ngokubanzi kuwo wonke umzimba kwiithishu ezininzi zomzimba kunye nolwelo. Ubomi besiqingatha seplasma yi-6-8 h. Ngaphezulu kwe-70% ichiza likhutshiwe lingatshintshanga kumchamo. Ukucocwa kwezintso kuncitshiswe ngama-57% kwimodareyitha yokungasebenzi kakuhle kwezintso kunye nama-77% ekungoneli kakhulu kwezintso.
Ukolulwa kwexesha le-QTC kwezinye izigulana kunye nokuphazamiseka kwesifo seswekile kukhokelele ekurhoxisweni kwechiza kumazwe amaninzi ukuze lisetyenziswe ngokwenkqubo. I-Gatifloxacin isasetyenziswa eMntla Melika kuphela njengesisombululo se-ophthalmic.
Imiphumela
I-Gatifloxacin ifakwe kakuhle kwi-gastrointestinal tract (ubukho bomlomo phantse i-100%), kunye nolawulo oluhambelanayo lwesidlo sakusasa se-continental, i-1050 kcal, ayizange ibe nefuthe ekufumanekeni kwayo. Umthamo oqhelekileyo ngu-400 mg od kwaye zombini iifom zomlomo kunye ne-intravenous zikhoyo.
Iziphumo ebezingalindelekanga eziqhelekileyo
Ukuba mandundu kosulelo lwamehlo
Ukucaphuka kwamehlo
Iintlungu zamehlo
Ukutshintsha incasa
