Ulwazi olusisiseko | |
Igama lemveliso | Doxycycline Hydrochloride |
Inombolo yeCAS. | 10592-13-9 |
Imbonakalo | Umgubo oMthubi |
IBanga | UkutyaIBanga |
Ukunyibilika kwamanzi | Inyibilika emanzini |
Ugcino | Umoya ongaphakathi,2-8°C |
Beka ubomi kwishelufa | iminyaka eyi-2 |
Iphakheji | 25kg/Igubu |
Ingcaciso yeMveliso
I-Doxycycline hydrochloride luhlobo lwe-hydrochloride lwe-doxycycline, isithinteli-ntsholongwane se-tetracycline esonwabisa ukusetyenziswa ngokubanzi kunyango lwezilwanyana kunye namayeza omntu ngenxa yobubanzi bayo kunye nomda obanzi wokhuseleko. Amalungu okuqala eklasi ye-tetracycline ahlukaniswe kwiintlobo ezininzi zebhaktheriya ukusuka kwi-Streptomyces ye-genus kwi-1940 kunye ne-1950. Ukususela ngelo xesha, iindidi ze-tetracycline zifunyenwe, zombini ziveliswa ngokwemvelo (umzekelo, i-chlortetracycline) kunye ne-semisynthetic (umzekelo, i-doxycycline kunye ne-tetracycline). I-Doxycycline yafunyaniswa ngo-1967 kwaye yenze uphando olubanzi, ngenxa yeempawu zayo zokulwa neentsholongwane kunye nemiphumo enayo kwi-physiology yezinto eziphezulu..
Isicelo
I-Doxycycline inesicelo esibalulekileyo kunyango lweemeko eziqhelekileyo ezingapheliyo, ezifana ne-acne kunye ne-rosacea; nangona kunjalo ukusetyenziswa kwayo kuluhlu lwezifo ezosulelayo ezingaqhelekanga, kuquka oko uHolmes et al achaza ngokuthi "ibhaktheriya ye-atypical", inike i-doxycycline udumo oluthile njenge "chiza elimangalisayo" okanye "isixhobo esiyimfihlo sikagqirha wezifo ezosulelayo". Ngaphandle kokunyangwa kwezizathu eziqhelekileyo zosulelo lokuphefumla kunye ne-genitourinary tract, ezinye zezicelo zayo ezibanzi kwakhona zizifo ezifana nosulelo lwe-rickettsial, i-leptospirosis, i-malaria, i-brucellosis, kunye nenani lezifo ezithathelwana ngesondo akufanele zithathwe ngaphantsi. Kananjalo ineentlobo ngeentlobo izicelo zamazinyo.Kwakhona kukho ukwanda kwe-30% kwinani lemigqaliselo elandela i-anthrax bioterrorism scares kwi-2000-2001.10 Ukongeza kwi-anthrax, i-doxycycline ingaba nesicelo kwimeko yezinye ii-agent ze-bioterrorist ezisetyenziswayo, ezifana ne-tularaemia kunye nesibetho.1 Ukusetyenziswa kwexesha elizayo isenokubandakanya unyango lwezinye izifo, ezifana ne-lymphatic filariasis, apho kubonakala ngathi kunentshukumo echasene ne-endosymbiotic bacteria ye-filariae ethile..