Inkcazelo emfutshane:
Inombolo ye-CAS: 15826-37-6
Ifomula yemolekyuli: C23H17NaO11
ubunzima bemolekyuli: 492.37
Ubume beKhemikhali:
| Ulwazi olusisiseko | |
| Igama lemveliso | Ityuwa yeCromolyn Disodium |
| Inombolo yeCAS. | 15826-37-6 |
| Imbonakalo | Mhlophe ukuya kwi-Off-White Powder |
| Ugcino | 2-8°C |
| Beka ubomi kwishelufa | iminyaka eyi-2 |
| Iphakheji | 25kg/Igubu |
Ingcaciso yeMveliso
Isodium cromoglycate yityuwa yesodium kunye nemarike eqhelekileyo evela kwi-cromoglicic acid, eyikhompawundi yokwenziwa, kwaye njengesixhobo sokuzinzisa iiseli zemast. Iyakwazi ukuthintela i-antigen-induced bronchospasms, kwaye ke isetyenziselwa ukunyanga i-asthma kunye ne-rhinitis ye-allergic. Inokusetyenziswa kwakhona njengesisombululo se-ophthalmic kunyango lwe-conjunctivitis kunye ne-systemic mastocytosis kunye ne-ulcerative colitis. Iyakwazi ukuthintela i-degranulation yeeseli zemast, ikhusela ngakumbi ukukhululwa kwe-histamine kunye ne-student-reacting substance ye-anaphylaxis (SRS-A), abalamli bohlobo lwe-alergic reaction. Kwakhona iyakwazi ukuthintela ukukhutshwa kwe-leukotrienes evuthayo kunye nokuthintela ukungena kwe-calcium.
Isicelo seMveliso
Isetyenziselwa ukuthintela ukuqala kwe-asthma ye-allergies, ukuphucula iimpawu ze-subjective, kunye nokwandisa ukunyamezela kwezigulane ukwenza umthambo. Kwizigulane ezithembele kwi-corticosteroids, ukuthatha le mveliso kunokunciphisa okanye ukuyeka ngokupheleleyo. Uninzi lwabantwana abane-asthma ye-refractory engapheliyo abasebenzisa le mveliso banokukhululeka okuncinci okanye okupheleleyo. Xa isetyenziswe ngokudibanisa ne-isoproterenol, izinga elisebenzayo liphezulu kakhulu kunokuba lisetyenziswe lodwa. Kodwa le mveliso isebenza ngokucothayo kwaye kufuneka isetyenziswe ngokuqhubekayo kangangeentsuku ezininzi ngaphambi kokuba isebenze. Ukuba isifo sele senzeke, amayeza asoloko engasebenzi. Izifundo zeklinikhi ziye zafumanisa ukuba i-cromolyte ye-sodium ayisebenzi kuphela kwi-asthma ye-allergies, edlala indima enkulu kwizinto eziphazamisayo, kodwa nakwi-asthma engapheliyo, apho iziphumo ze-allergies zingabalulekanga. Isetyenziselwa i-rhinitis ye-alergic kunye ne-hay fever yexesha elithile, inokulawula ngokukhawuleza iimpawu. Ukusetyenziswa kwangaphandle kwe-ointment kwi-eczema ye-aleji engapheliyo kunye nolusu oluthile lwe-pruritus lubonise iziphumo ezibalulekileyo zonyango. I-2% ukuya kwi-4% yamathontsi eliso afanelekile kwi-hay fever, conjunctivitis, kunye ne-vernal keratoconjunctivitis.
