Inkcazelo emfutshane:
Inombolo yeCAS:62893-20-3 693878-84-7
Ifomula yemolekyuli: C25H26N9Na08S2 C8H10NNa05S
Ubume bekhemikhali:
| Ulwazi olusisiseko | |
| Igama lemveliso | I-Cefoperazone sodium + sulbactam sodium (1:1/2:1) |
| Umlinganiswa | Umgubo |
| Inombolo yeCAS. | 62893-20-3 693878-84-7 |
| Umbala | Umgubo omhlophe ukuya kumdaka okhanyayo |
| Beka ubomi kwishelufa | iminyaka eyi-2 |
| Umgangatho weBanga | IBanga lobuNyango |
| Ubunyulu | 99% |
| Inombolo yeCAS. | 62893-20-3 |
| Iphakheji | 10kg/igubu |
Inkcazo
Inkcazo:
I-Cefoperazone sodium + sulbactam sodium (1: 1/2: 1) i-parenterally-active, i-β-lactamase inhibitor esandul 'ukuqaliswa njenge-1: imveliso ye-1 yokudibanisa kunye ne-cefoperazone. Njenge-clavulanic acid, i-ejenti yokuqala yolu hlobo ukuqaliswa, i-sulbactam iphakamisa ukusebenza kwe-antibiotics ye-β-lactam ngokuchasene neentlobo ezixhathisayo.
Ukusetyenziswa:
I-semi-synthetic β-lactamase inhibitor. Isetyenziswa ngokudibeneyo ne-β-lactam antibiotics njenge-antibacterial.
I-Cefoperazone ityuwa ye-sodium yi-cephalosporin antibiotic yokuthintela i-rMrp2-mediated [3H] E217βG yokuthatha nge-IC50 ye-199 μM. Ithagethi: I-Antibacterial Cefoperazone yintsholongwane, i-semisynthetic, i-spectrum ebanzi, i-parenteral cephalosporin antibiotics yokulawulwa kwe-intravenous okanye intramuscular. Emva kokulawulwa kwe-intravenous ye-2 g ye-Cefoperazone, amanqanaba kwi-serum avela kwi-202μg / mL ukuya kwi-375 μg / mL kuxhomekeke kwixesha lokulawulwa kweziyobisi. Emva kwesitofu se-intramuscular ye-2 g ye-Cefoperazone, inqanaba eliphakathi kwe-serum ye-serum yi-111 μg / mL kwiiyure ze-1.5. Kwiiyure ze-12 emva kokuthatha i-dosing, amanqanaba aphakathi kwe-serum asese-2 ukuya kwi-4 μg / mL. I-Cefoperazone i-90% ibotshelelwe kwiiprotheni ze-serum.
