Inkcazelo emfutshane:
Inombolo yeCAS: 137-88-2
Ifomula yemolekyuli: C14H20Cl2N4
ubunzima bemolekyuli: 315.24
Ubume beKhemikhali:
| Ulwazi olusisiseko | |
| Igama lemveliso | I-Amprolium Hydrochloride |
| IBanga | Ibanga lokutyisa |
| Imbonakalo | Umgubo weCrystalline oMhlophe |
| Isivavanyi | 99% |
| Beka ubomi kwishelufa | iminyaka eyi-2 |
| Ukupakisha | 25kg/igubu |
| Imeko | Gcina kwindawo epholileyo, eyomileyo, emnyama kwisitya esivalwe ngokuqinileyo okanye isilinda. |
Ukuqaliswa kwe-Amprolium Hydrochloride
I-Amprolium i-thiamine analog kunye ne-antiprotozoal agent ephazamisa i-thiamine metabolism kwaye inqanda i-carbohydrate synthesis. Ngokukhuphisanayo inqanda ukufunyanwa kwe-thiamine yi-E. tenella schizonts kunye neeseli ze-chick host intestinal (Kis = 7.6 kunye ne-326 μM, ngokulandelanayo). Ikwanqanda ukubunjwa kwe-hexose kunye nokusetyenziswa kwe-pentose ex vivo kwi-lysed rat erythrocytes kunye nesibindi, izintso, intliziyo, kunye ne-intestinal tissue homogenates emva kokulawulwa kokutya. I-Amprolium (1,000 ppm kwisondlo) inqanda ukuphuma kwe-oocyst kunye ne-sporulation ye-Eimeria maxima, E. brunetti, kunye ne-E. acervulina kumantshontsho asulelekileyo. Ikwanciphisa isilonda kunye namanqaku e-oocyst kunye nokufa kwamantshontsho awosulelwe yi-E. tenella kulandela ukulawulwa kokutya kwedosi ye-125 ppm. I-Amprolium (i-100 μM) yenza i-apoptosis kwi-PC12 iiseli ze-adrenal rat kwaye inyuse izinga le-caspase-3 ecatshulweyo. Uqulunqo oluqulethe i-amprolium lusetyenziswe njenge-coccidiostats ekuqhubeni iinkukhu.
Ukusetyenziswa kweAmprolium Hydrochloride
I-Amprolium Hydrochloride inomsebenzi olungileyo ngokuchasene ne-Eimeria tenella kunye ne-E. acervulina kwiinkukhu kwaye ingasetyenziselwa njenge-agent yonyango kwezi ziphilayo. Inomsebenzi we-marginal kuphela okanye umsebenzi obuthathaka ngokuchasene ne-E. maxima, E. mivati, E. necatrix, okanye i-E. brunetti. Ihlala isetyenziswa ngokudibeneyo nezinye ii-agent (umz., i-ethopabate) ukuphucula ulawulo oluchasene nezo ziphilayo.
Kwiinkomo, i-amprolium inemvume yonyango kunye nokuthintela i-E. bovis kunye ne-E. zurnii kwiinkomo kunye namathole.
I-Amprolium isetyenziswe kwizinja, iihagu, iigusha, kunye neebhokhwe ukulawula i-coccidiosis, nangona kungekho mveliso evunyiweyo e-USA kwezi ntlobo.
