Inkcazelo emfutshane:
Inombolo ye-CAS: 1197-18-8
Ifomula yemolekyuli: C8H15NO2
ubunzima bemolekyuli: 157.21
Ubume bekhemikhali:
| Ulwazi olusisiseko | |
| Igama lemveliso | Tranexamic Acid |
| IBanga | IBanga leCosmetic |
| Imbonakalo | Imhlophe okanye iphantse imhlophe, i-crystalline powder |
| Isivavanyi | 99% |
| Beka ubomi kwishelufa | iminyaka eyi-2 |
| Ukupakisha | 25kg/igubu |
| Iipropati zeMichiza | Inyibilika ngokukhululekileyo emanzini nakwi glacial acetic acid kwaye iyanyibilika kancinane kwi ethanol kwaye ayinyibiliki kwi ether. |
Inkcazo
I-Tranexamic acid iphuma kwi-aminomethylbenzoic acid, kunye nohlobo lwamachiza e-antifibrinolytic ukumisa ukopha. Indlela ye-hemostasis ye-tranexamic acid ifana ne-aminocaproic acid kunye ne-aminomethylbenzoic acid, kodwa umphumo unamandla. Amandla ngamaxesha angama-7 ukuya kwe-10 ye-aminocaproic acid, amaxesha e-2 e-aminomethylbenzoic acid, kodwa ubuthi bufana.
Ubume bemichiza ye-tranexamic acid ifana ne-lysine, inhibition yokhuphiswano lwe-plasmin yokuqala kwi-fibrin adsorption, ukuthintela ukusebenza kwabo, ukukhusela iprotheni yefiber ukuba ingathotywanga nge-plasmin kwaye ichithe, ekugqibeleni ifikelele kwi-hemostasis. Isebenza kunyango lwefiber fibrinolytic hyperthyroidism ebukhali okanye engapheliyo, ebangelwa kukopha, njengokuphuma kwe-obstetric, ukopha kwezintso, ukopha kwe-prostate, i-hemophilia, i-pulmonary tuberculosis hemoptysis, ukopha kwesisu, emva kokusebenza kwesibindi, imiphunga. , udakada kunye nokunye ukopha kwe-viscera; nayo ingasetyenziselwa utyando xa ukopha okungaqhelekanga njl.
I-Clinical tranexamic acid inefuthe elibalulekileyo kwi-insect bites isifo, i-dermatitis kunye ne-eczema, i-purpura elula, i-urticaria engapheliyo, i-artificial sex urticaria, ukuqhuma okunetyhefu kunye nokuqhuma. Kwaye kwakhona kunempembelelo ethile kwi-erythroderma, scleroderma, systemic lupus erythematosus (SLE), i-Erythema multiforme, i-shingles kunye ne-alopecia areata. Unyango lwe-angioedema ye-hereditary effect nayo ilungile. Kunyango lwe-Chloasma, iyeza eliqhelekileyo lisebenza malunga neeveki ezi-3, lisebenza ngokubonakalayo iiveki ezi-5, ikhosi yeentsuku ezingama-60. Inikwe ngomlomo kwiidosi ze-0.25 ~ 0.5 g, ngosuku 3 ~ 4 amaxesha. Izigulana ezimbalwa zinokuba nesicaphucaphu, ukudinwa, ukurhawuzelela, ukungakhululeki kwesisu, kunye neziphumo ebezingalindelekanga zorhudo emva kokunyamalala kweempawu zokurhoxa.
Iimpawu
Ukopha okwahlukeneyo okubangelwa yi-hyperfibrinolysis ephambili okanye engapheliyo, yendawo okanye yesistim; imeko yesibini ye-hyperfibrinolytic ebangelwa kukusasazwa kwe-intravascular coagulation. Ngokuqhelekileyo musa ukusebenzisa le mveliso phambi kokuba heparinization.
Umothuko okanye ukopha ukopha kwizicubu kunye namalungu anezixhobo ezininzi ze-plasminogen ezifana ne-prostate, urethra, imiphunga, ingqondo, isibeleko, i-adrenal glands, kunye ne-thyroid.
Umchasi we-tissue plasminogen activator (t-PA), i-streptokinase, kunye ne-urokinase.
I-Fibrinolytic hemorrhage ebangelwa ukukhupha isisu, ukukhupha i-placenta kwangethuba, ukuzala umntwana oshonile kunye ne-amniotic fluid embolism; kunye nokunyuka kwe-menorrhagia okubangelwa yi-pathological intrauterine fibrinolysis.
I-Cerebral neuropathy ukopha kancinci, njenge-subarachnoid hemorrhage kunye ne-intracranial aneurysm hemorrhage, umphumo we-Amstat kule meko ungcono kunezinye i-anti-fibrinolytic agents. Ingqwalasela ekhethekileyo kufuneka ihlawulwe kumngcipheko we-cerebral edema okanye i-cerebral infarction.Kwizigulane ezinzima ezinezibonakaliso zotyando, le mveliso ingasetyenziselwa kuphela njengeyeza elincedisayo.
Kunyango lwe-angioneurotic edema ye-hereditary, inokunciphisa inani kunye nobukhulu beziqephu.
Isetyenziswa kwizigulane ezine-hemophilia ukopha kwazo okusebenzayo kudityaniswe namanye amachiza.
Izigulane ze-Hemophilia ezine-factor VIII okanye i-factor IX yokusilela ekukhutshweni kwamazinyo okanye utyando lomlomo kwimeko yokuphuma kwegazi.
