Inkcazelo emfutshane:
Inombolo ye-CAS: 64-75-5
Ifomula yemolekyuli:C22H25ClN2O8
ubunzima bemolekyuli:480.9
Ubume beKhemikhali:
| Ulwazi olusisiseko | |
| Igama lemveliso | Tetracycline hydrochloride |
| IBanga | Ibakala le-Pharma |
| Imbonakalo | Umgubo wekristale otyheli |
| Isivavanyi | 99% |
| Beka ubomi kwishelufa | iminyaka eyi-2 |
| Ukupakisha | 25kg/igubu |
| Imeko | Itywinwe kwindawo eyomileyo, Gcina kwisikhenkcisi, ngaphantsi kwe -20°C |
Inkcazo
I-Tetracycline sisithinteli-ntsholongwane esibanzi esithintela ukukhula kwebhaktheriya ngokuthintela ukwakheka kweeprotheyini. Ibophelela kwindawo enye kwi-30S ribosomal subunit ethintela uncamathiselo lwe-aminoacyl tRNA kwindawo yokwamkela i-ribosomal. Isetyenziswa kwi-cell biology njenge-arhente ekhethiweyo kwiinkqubo zenkcubeko yeeseli. I-Tetracycline inetyhefu kwiiseli ze-prokaryotic kunye ne-eukaryotic kwaye ikhethela iiseli ezine-bacterial tetR gene, ekwaziyo ukumelana ne-antibiotic.
Usebenzisa
I-Tetracycline hydrochloride ityuwa elungiselelwe ukusuka kwi-tetracycline ithatha inzuzo yeqela elisisiseko le-dimethylamino elenza i-protonates kwaye yenza ngokukhawuleza ityuwa kwi-hydrochloric acid solutions. I-hydrochloride yindlela ekhethwayo yokwenziwa kwezicelo zamachiza. I-Tetracycline hydrochloride inomsebenzi obanzi we-antibacterial kunye ne-antiprotozoan kwaye isebenza ngokubophelela kwi-30S kunye ne-50S ye-ribosomal sub-unit, i-protein synthesis.
I-Tetracycline hydrochloride isetyenziselwa ukwenza i-apoptosis kwi-osteoclasts. Isetyenziselwa ukunyanga amaqhakuva kunye nolunye usulelo lwesikhumba, usulelo lwendlela yokuphefumla njengenyumoniya, amalungu angasese, usulelo lokuchama, i-leptospirosis, i-helicobacter pylori, i-taxoplasmosis, i-mycoplasma, i-psittacosis yenja kunye neekati. Ikwasebenza ngokufanelekileyo kwizilwanyana ezinosulelo olubangelwa ngamakhalane. Ikwaluncedo kwizicelo zenkcubeko yeseli.
Ngelixa i-tetracycline isasetyenziswa njenge-antimicrobial, uninzi lweekliniki zezilwanyana ezincinci zikhetha i-doxycycline kwaye iikliniki zezilwanyana ezinkulu zikhetha i-oxytetracycline xa i-tetracycline iboniswa ukunyanga izifo ezithintekayo. Olona setyenziso luxhaphakileyo lwe-tetracycline HCl namhlanje ludityaniswe ne-niacinamide kunyango lwezigulo ezithile zolusu ezikhusela umzimba kwizinja, ezifana ne-pemphigus.
Amachiza ezilwanyana kunye noNyango
Ngelixa i-tetracycline isasetyenziswa njenge-antimicrobial, uninzi lweekliniki zezilwanyana ezincinci zikhetha i-doxycycline kwaye iikliniki zezilwanyana ezinkulu zikhetha i-oxytetracycline xa i-tetracycline iboniswa ukunyanga izifo ezithintekayo. Olona setyenziso luxhaphakileyo lwe-tetracycline HCl namhlanje ludityaniswe ne-niacinamide kunyango lwezigulo ezithile zolusu ezikhusela umzimba kwizinja, ezifana ne-pemphigus.
