Ulwazi olusisiseko | |
Igama lemveliso | Ithebhulethi yeMelatonin |
IBanga | Ibakala lokutya |
Imbonakalo | Njengeemfuno zabathengi uMjikelo, Oval, Oblong, Unxantathu, Idayimane kunye nezinye iimilo ezikhethekileyo zonke ziyafumaneka. |
Beka ubomi kwishelufa | I-2-3 iminyaka, ngokuxhomekeke kwimeko yevenkile |
Ukupakisha | Ubuninzi, iibhotile, iipakethi zeblister okanye iimfuno zabathengi |
Imeko | Gcina kwizikhongozeli eziqinileyo, ezikhuselwe ekukhanyeni. |
Inkcazo
I-Melatonin yi-hormone ye-amine eveliswa ngokuyinhloko yi-pineal gland kwizilwanyana ezanyisayo nakubantu.
Ukukhutshwa kweMelatonin kunesingqisho se-circadian kwaye ngokubanzi kufikelela kwincopho yayo ngo-2-3 am. Inqanaba le-melatonin ebusuku lichaphazela ngokuthe ngqo umgangatho wokulala. Njengoko ubudala bukhula, ngakumbi emva kweminyaka engama-35 ubudala, i-melatonin eveliswa ngumzimba ngokwawo iyancipha kakhulu, ngokuhla okuqhelekileyo kwe-10-15% yonke iminyaka eyi-10, okukhokelela kukuphazamiseka kokulala kunye nochungechunge lweengxaki zokusebenza, ngelixa amanqanaba e-melatonin ehla kwaye ubuthongo buyancipha. Ngomnye weempawu ezibalulekileyo zokuguga kwengqondo yomntu. Ke ngoko, ukongezelela i-melatonin evela ngaphandle komzimba kunokugcina inqanaba le-melatonin emzimbeni kwindawo encinci, ukulungelelanisa nokubuyisela isigqi se-circadian, kungenzi nje ukulala nzulu kunye nokuphucula umgangatho wokulala, kodwa okona kubaluleke kakhulu, ukuphucula imeko yokusebenza komzimba wonke kwaye ukuphucula ubomi. umgangatho kwaye ucothise inkqubo yokuguga.
Umsebenzi
1. Imiphumo yokuguga ye-melatonin
I-Melatonin ikhusela ukwakheka kweeseli, ikhusela umonakalo we-DNA, kwaye inciphisa amanqanaba eperoxide emzimbeni ngokukhupha iiradicals zasimahla, i-antioxidants, kunye nokuthintela i-lipid peroxidation.
2. Impembelelo ye-immune-modulating ye-melatonin
I-Melatonin inokuchasana neziphumo zokuxinzezeleka kwe-induced immunosuppressive kwiimpuku ezibangelwa yimiba yengqondo (ixhala elibukhali), kwaye ithintele ukukhubazeka nokufa okubangelwa luxinzelelo olunzima olubangelwa zizinto ezosulelayo (idosi engaphantsi kwentsholongwane ye-cerebromyocardial virus).
3. Imiphumo ye-Anti-tumor ye-melatonin
I-Melatonin inokunciphisa ukubunjwa kwee-adducts ze-DNA ezibangelwa yi-chemical carcinogens (safrole) kunye nokukhusela umonakalo we-DNA.
Usetyenziso
1. Umntu omdala.
2. Abangalaliyo.
3. Abo banomgangatho ophantsi wokulala kwaye bavuswa ngokulula.