Ulwazi olusisiseko | |
Igama lemveliso | I-Lincomycin Hydrochloride |
IBanga | IBanga lezamayeza |
Imbonakalo | Umgubo wekristale omhlophe |
Isivavanyi | 99% |
Beka ubomi kwishelufa | iminyaka eyi-2 |
Ukupakisha | 25kg/igubu |
Imeko | igcinwe kwindawo epholileyo neyomileyo |
Inkcazo ye-Lincomycin HCL
I-Lincomycin hydrochloride ngumgubo omhlophe okanye omhlophe, oyikristale kwaye awunavumba okanye unevumba elibi. Izisombululo zayo zi-asidi kwaye ziyi-dextrorotatory. I-Lincomycin hydrochloride inyibilika ngokukhululekileyo emanzini; Inyibilika kwi-dimethylformamide kwaye kancinane kakhulu ukunyibilika kwithowuni ye-ace.
Umsebenzi
Isetyenziswa ikakhulu kunyango losulelo olubangelwa ziintsholongwane zeGram-positive ingakumbi iibhaktheriya ezixhathisa ipenicillin kwiGram-positive, isifo sokuphefumla kweenkukhu esibangelwa yiMycoplasma, inyumoniya yehagu enzootic, usulelo lweanaerobic olufana nenkukhu necrotizing enterocolitis.
Ingasetyenziselwa unyango lwe-treponema dysentery, toxoplasmosis kunye ne-actinomycosis yezinja kunye neekati.
Isicelo
I-Lincomycin sisithinteli-ntsholongwane se-lincosamide esivela kwi-actinomyces Streptomyces lincolnensis. Ikhompawundi enxulumeneyo, i-clindamycin, ithathwe kwi-lincomycin ngokusebenzisa ukubuyisela iqela le-7-hydroxy nge-athomu kunye ne-inversion ye-chirality.
Nangona iyafana kwisakhiwo, i-antibacterial spectrum, kunye nendlela yokusebenza kwi-macrolides, i-lincomycin iyasebenza ngokuchasene nezinye izinto eziphilayo ezibandakanya i-actinomycetes, i-mycoplasma, kunye nezinye iintlobo ze-Plasmodium. Ukulawulwa kwe-intramuscular ye-dose eyodwa ye-600 mg ye-Lincomycin ivelisa amanqanaba aphezulu e-serum ye-11.6 micrograms / ml kwimizuzu engama-60, kwaye igcina amanqanaba onyango kwii-17 kwiiyure ze-20, kwizinto ezininzi ezithintekayo zegram-positive. Ukukhutshwa kwe-Urinary emva kwesi sithako sisuka kwi-1.8 ukuya kwi-24.8 ekhulwini (ithetha: i-17.3 ekhulwini).
1. Ukwenziwa ngomlomo kukulungele ukunyanga izifo zokuphefumla, ukusuleleka kwisisu, ukusuleleka kwintsholongwane yabasetyhini, izifo ze-pelvic, izifo zesikhumba kunye nezicubu ezithambileyo ezibangelwa ubuthathaka beStaphylococcus aureus kunye neStreptococcus pneumoniae.
2. Ukongeza kunyango lwezi zifo zingentla, iifomula ezitofelweyo zifanelekile kunyango lwezifo ezinzima ezibangelwa yi-streptococcus, pneumococcus kunye ne-staphylococcus ezifana nonyango lwe-adjuvant yonyango lwe-septicemia, ithambo kunye nosulelo oludibeneyo, izifo ezingapheliyo zethambo kunye ne-Staphylococcus- i-acute hematogenous osteomyelitis.
3. I-Lincomycin hydrochloride isenokusetyenziswa kunyango lwezifo ezosulelayo kwizigulana ezingadibani nepenicillin okanye ezingakulungelanga ukulawulwa kwamachiza ohlobo lwepenicillin.