China OEM 112811-71-9 Ethyl 1-Cyclopropyl-6, 7-Difluoro-8-Methoxy-4-Oxo-1, 4-Dihydroquinoline-3-Carboxylate

Asiyi kuzama kuphela ukubonelela ngeenkonzo ezibalaseleyo kuye wonke umthengi, kodwa sikulungele ukufumana naziphi na iingcebiso ezinikezelwa ngabathengi bethu base China OEM 112811-71-9 Ethyl 1-Cyclopropyl-6, 7-Difluoro-8-Methoxy- I-4-Oxo-1, 4-Dihydroquinoline-3-Carboxylate, Kwifemu yethu enomgangatho olungileyo ekuqaleni njengesaci sethu, senza izinto ezithengiweyo ezenziwe ngokupheleleyo eJapan, ukusuka ekuthengeni izixhobo ukuya ekusetyenzweni kwazo. Oku kubenza bakwazi ukusetyenziswa ngoxolo lwengqondo oluqinisekileyo.
Asiyi kuzama kuphela ukubonelela ngeenkonzo ezibalaseleyo kuye wonke umthengi, kodwa sikulungele ukufumana naziphi na iingcebiso ezinikezelwa ngabathengi bethu.China 112811-71-9 kunye neGatifloxacin Ethylester, Namhlanje, besinomdla omkhulu kunye nokunyaniseka ukuzalisekisa ngakumbi iimfuno zabathengi bethu behlabathi ngomgangatho olungileyo kunye noyilo loyilo. Samkela ngokupheleleyo abathengi abavela kwihlabathi liphela ukuba baseke ubudlelwane beshishini obuzinzile nobunenzuzo ngokufanayo, ukuba nekamva eliqaqambileyo kunye.

Ingcaciso yeMveliso

I-Gatifloxacin yeyodidi lwamachiza aziwa ngokuba yi-quinolone antibiotics kwaye isetyenziselwa ukunyanga izifo ze-sinus, imiphunga, okanye i-urinary tract kunye ne-bacterial infection. kunye ne-gatifloxacin ziquka isicaphucaphu, i-vaginitis (ukucaphuka okanye ukudumba kwelungu lobufazi), urhudo, intloko ebuhlungu, isiyezi, kunye nokubetha kwentliziyo okungaqhelekanga. Ngokuqhelekileyo, i-gatifloxacin isetyenziswe kubantu abangaphenduliyo kwezinye iindlela zonyango ze-AOM.
Kwisifundo esinye, i-gatifloxacin yafaniswa ne-amoxicillin / i-clavulanate kunyango lwe-otitis media (OM) kunye ne-AOM kwiintsilelo zonyango kubantwana.Iintsana ezingamakhulu amathathu namashumi amahlanu anesine kunye nabantwana abane-OM okanye i-AOM ephindaphindiweyo bafumana i-gatifloxacin okanye i-amoxicillin / clavulanate. Iziphumo zabonisa ukuba omabini amachiza anyamezeleke kakuhle; esona siphumo sixhaphakileyo sisirhudo.Abaphandi bagqibe kwelokuba unyango nge-gatifloxacin kanye yonke imihla lwalusebenza njenge-amoxicillin/clavulanate kabini yonke imihla.Kwezinye iincwadi zonyango, i-gatifloxacin iqatshelwe njengendlela yonyango lodidi lwesithathu kwi-AOM.

Ukusetyenziswa kwezamayeza

I-spectrum ibandakanya i-Acinetobacter spp kunye ne-Aeromonas spp, kodwa ayisebenzi kakhulu ngokuchasene ne-Ps. i-aeruginosa kunye nezinye iintonga ezingenayo i-Gram-negative. Isebenza ngakumbi kwiintlobo ze-staphylococci ezinokuthi zichaphazeleke kwi-methicillin kuneentlobo ezikwaziyo ukumelana ne-methicillin. Ikwasebenza ngokuchasene neChlamydia, Mycoplasma kunye neLegionella spp. kwaye unomsebenzi othile ochasene ne-anaerobes.
Iphantse ifunxe ngokupheleleyo xa inikwe ngomlomo kwaye isasazwa ngokubanzi kuwo wonke umzimba kwiithishu ezininzi zomzimba kunye nolwelo. Ubomi besiqingatha seplasma yi-6-8 h. Ngaphezulu kwe-70% ichiza likhutshiwe lingatshintshanga kumchamo. Ukucocwa kwezintso kuncitshiswe ngama-57% kwimodareyitha yokungasebenzi kakuhle kwezintso kunye nama-77% ekungoneli kakhulu kwezintso.
Ukolulwa kwexesha le-QTC kwezinye izigulana kunye nokuphazamiseka kwesifo seswekile kukhokelele ekurhoxisweni kwechiza kumazwe amaninzi ukuze lisetyenziswe ngokwenkqubo. I-Gatifloxacin isasetyenziswa eMntla Melika kuphela njengesisombululo se-ophthalmic.

Imiphumela

I-Gatifloxacin ifakwe kakuhle kwi-gastrointestinal tract (ubukho bomlomo phantse i-100%), kunye nolawulo oluhambelanayo lwesidlo sakusasa se-continental, i-1050 kcal, ayizange ibe nefuthe ekufumanekeni kwayo. Umthamo oqhelekileyo ngu-400 mg od kwaye zombini iifom zomlomo kunye ne-intravenous zikhoyo.
Iziphumo ebezingalindelekanga eziqhelekileyo
Ukuba mandundu kosulelo lwamehlo
Ukucaphuka kwamehlo
Iintlungu zamehlo
Ukutshintsha incasa

Asiyi kuzama kuphela ukubonelela ngeenkonzo ezibalaseleyo kuye wonke umthengi, kodwa sikulungele ukufumana naziphi na iingcebiso ezinikezelwa ngabathengi bethu base China OEM 112811-71-9 Ethyl 1-Cyclopropyl-6, 7-Difluoro-8-Methoxy- I-4-Oxo-1, 4-Dihydroquinoline-3-Carboxylate, Kwifemu yethu enomgangatho olungileyo ekuqaleni njengesaci sethu, senza izinto ezithengiweyo ezenziwe ngokupheleleyo eJapan, ukusuka ekuthengeni izixhobo ukuya ekusetyenzweni kwazo. Oku kubenza bakwazi ukusetyenziswa ngoxolo lwengqondo oluqinisekileyo.
China OEMChina 112811-71-9 kunye neGatifloxacin Ethylester, Namhlanje, besinomdla omkhulu kunye nokunyaniseka ukuzalisekisa ngakumbi iimfuno zabathengi bethu behlabathi ngomgangatho olungileyo kunye noyilo loyilo. Samkela ngokupheleleyo abathengi abavela kwihlabathi liphela ukuba baseke ubudlelwane beshishini obuzinzile nobunenzuzo ngokufanayo, ukuba nekamva eliqaqambileyo kunye.