Inkcazelo emfutshane:
Inombolo ye-CAS: 74578-69-1
Ifomula yemolekyuli: C18H19N8NaO7S3
Ubunzima bemolekyuli: 578.57
Ubume bekhemikhali:
| Ulwazi olusisiseko | |
| Igama lemveliso | ceftriaxone sodium |
| Inombolo yeCAS. | 74578-69-1 |
| Imbonakalo | Umgubo omhlophe ukuya kumhlophe |
| IBanga | Pharma iBanga |
| Ugcino | 4°C, khusela ekukhanyeni |
| Beka ubomi kwishelufa | iminyaka eyi-2 |
| Iphakheji | 25kg/Igubu |
Ingcaciso yeMveliso
I-Ceftriaxone yi-cephalosporin (i-SEF i-spor ephantsi) esetyenziselwa ukunyanga iimeko ezifana nosulelo lwendlela yokuphefumula ephantsi, ukusuleleka kwesikhumba kunye nolusu, ukusuleleka kwi-urinary tract, isifo se-pelvic, i-septicemia ye-bacterial, i-bone and joint infections, kunye ne-meningitis.
Ukusetyenziswa kweKlinikhi
I-Ceftriaxone sodium yi-β-lactamase-resistantcephalosporin kunye ne-serum ende ye-half-life.Idosi ye-Once-day yanele izibonakaliso ezininzi. Izinto ezimbini ezinegalelo kwixesha elide lesenzo se-ceftriaxone: iprotheyini ephezulu ebophelela kwiplasma kunye nokuphuma kancinci kwe-urinary. I-Ceftriaxone ikhutshelwa kwi-bile kunye nomchamo. Ukukhutshwa komchamo wayo akuchatshazelwa yiprobenecid. Ngaphandle komthamo ophantsi wokusasazwa kwayo, ifikelela kulwelo lwe-cerebrospinal kugxininiso olusebenzayo kwi-meningitis. I-pharmacokinetics engahambelaniyo iyabonwa.
I-Ceftriaxone iqulethe i-heterocyclic system ene-acidic kakhulu kwiqela le-3-thiomethyl. Le ringsystem ye-dioxotriazine engaqhelekanga ikholelwa ukuba inikezela ngeempawu ezizodwa ze-pharmacokinetic zale arhente. I-Ceftriaxone inxulunyaniswe ne-sonographical "sludge," okanye i-pseudolithiasis, kwi-gallbladder kunye ne-bile duct eqhelekileyo. Iimpawu zecholecystitis zinokuvela kwizigulana ezisesichengeni, ngakumbi ezo zithatha ixesha elide okanye idosi ephezulu yonyango lwe-ceftriaxone. I-Theculprit ichongiwe njenge-calcium chelate.
I-Ceftriaxone ibonisa i-antibacterial egqwesileyo ebanzi ebanzi ngokuchasene ne-Gram-positive kunye ne-Gram-negativeorganisms. Ixhathisa kakhulu kwii-β-lactamases ezininzi zechromosomally andplasmid-mediated. Umsebenzi we-ceftriaxoneagainst Enterobacter, Citrobacter, Serratia, indole-positiveProteus, kunye nePseudomonas spp. ichukumisa ngokukodwa. I-Itis ikwasebenza kunyango lwe-ampicillin-resistant gonorrhea kunye nosulelo lomkhuhlane we-H. kodwa lusebenza kancinci kune-cefotaxime ngokuchasene ne-Gram-positive bacteria kunye ne-B.fragilis.
