Inkcazelo emfutshane:
Inombolo ye-CAS: 83905-01-5
Ifomula yemolekyuli: C38H72N2O12
ubunzima bemolekyuli: 748.98
Ubume beKhemikhali:
| Ulwazi olusisiseko | |
| Igama lemveliso | Azithromycin |
| Inombolo yeCAS. | 83905-01-5 |
| Imbonakalo | umgubo omhlophe wekristale |
| IBanga | Pharma iBanga |
| Ubunyulu | 96.0-102.0% |
| ukuxinana | 1.18±0.1 g/cm3(Kuxelwe kwangaphambili) |
| ifomu | Icocekile |
| Uzinzo | Izinzile. Ayihambelani ne-oxidizing agents ezinamandla |
| Iphakheji | 25kg/igubu |
Ingcaciso yeMveliso
I-Azithromycin yayiyeyokuqala yee-azalides kwaye yayiyilelwe ukuphucula uzinzo kunye nesiqingatha sebhayoloji ye-erythromycin A, kunye nokuphucula umsebenzi ochasene ne-Gram negative bacteria. I-Azithromycin sisibulali-zintsholongwane esisebenza ixesha elide se-macrolide ngokwesakhiwo esinxulumene ne-erythromycin A (EA), ene-nitrogen efakwe endaweni ye-methyl kwindawo ye-9a kwiringi ye-aglycone.
Isicelo seMveliso
I-Azithromycin yeye-antibiotics ye-broad-spectrum kwaye iyi-antibiotic yesizukulwana sesibini se-macrolides. Ezona ziphumo ziphambili ziiphecana zokuphefumla, ulusu kunye nosulelo lwezicubu ezithambileyo ezibangelwa ziibhaktheriya ezinobuthathaka kunye nezifo ezosulelayo ze-chlamydia. Inempembelelo entle yonyango kusulelo olubukhali lwe-bronchial olubangelwa yintsholongwane yomkhuhlane, i-pneumococci, kunye ne-Moraxella catarrhalis, kunye nesifo esingapheliyo semiphunga esinenyumoniya.Ukongeza kwezi meko zingasentla, i-azithromycin ikwalichiza elisetyenziswa ngokuqhelekileyo lokuthintela umkhuhlane wamathambo. Ukuba isetyenziswe ngokungqongqo phantsi kolawulo logqirha, inokudibaniswa kunye ne-dexamethasone amalungiselelo e-acetate ukuthintela ngokufanelekileyo isifo. Isenokusetyenziselwa usulelo olulula lwangasese olubangelwa yi-Neisseria gonorrhoeae enganyangekiyo ngamachiza, kunye nezifo ezifana ne-chancre ebangelwa yi-Haemophilus duke.Nangona kunjalo, kufuneka kuqatshelwe ukuba ukuba umntu uyala kwi-azithromycin, i-erythromycin kunye nezinye iziyobisi ze-macrolide, ukusetyenziswa kwazo kufuneka kuthintelwe. Abantu abanembali ye-cholestatic jaundice kunye nokungasebenzi kakuhle kwesibindi akufanele basebenzise eli liyeza. Abasetyhini abakhulelweyo kunye nabasetyhini abancancisayo kufuneka balandele ngokungqongqo iingcebiso zonyango kwaye basebenzise amayeza ngononophelo ukunqanda ukuchaphazela usana okanye usana.
